The Ghostbusters are called in to deal with one of the most famous and thematically-appropriate ghosts: the restless spirit of the massively influential innovator of literary horror, H.P. Lovecraft.

EXT. THE QUAD, MISKATONIC UNIVERSITY – NIGHT

The gaseous, glowing ghost of H.P. LOVECRAFT looms over all four Ghostbusters, stretching and twisting to impossible proportions, tentacles and antennae slithering out of him like growing shadows. A dry, howling, unnatural wind swirls through the Quad.

LOVECRAFT
CHATTERING INTERBREEDERS! FOUL, GUFFAWING APES! I WILL CLEANSE–

VENKMAN
Yeesh, who knew Poe was such a dick?